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目的 比较5.0T MRI和3.0T MRI颅脑常规扫描序列的图像质量。方法 招募35例健康志愿者,接受5.0T MRI和3.0T MRI颅脑常规扫描,扫描序列包括T2WI、T1WI、T_2-FLAIR、DWI序列。由2位医师采用双盲法对图像进行分析,定量指标包括信噪比(SNR)、对比度噪声比(CNR),定性指标包括图像质量、伪影、灰白质清晰度,比较不同场强下图像质量的差异。应用组内相关系数(ICC)评价定量指标一致性,应用Kappa一致性分析评价定性指标一致性。结果定量分析显示,在T2WI和T1WI序列中,5.0T MRI的SNR在半卵圆中心区额叶脑灰质/白质、壳核、脑桥及小脑中脚显著高于3.0T MRI,差异有统计学意义(P<0.01);在T_2-FLAIR序列中,3.0T MRI的壳核SNR优于5.0T MRI,差异有统计学意义(P<0.01);在T2WI和T_2-FLAIR序列中,5.0T MRI的灰白质CNR优于3.0T MRI,差异有统计学意义(P<0.01),而在T1WI序列中5.0T MRI与3.0T MRI的CNR比较差异无统计学意义(P>0.05)。定性分析显示5.0T MRI所有序列的整体图像质量均优于3.0T MRI;5.0T MRI DWI序列的伪影更少、灰白质清晰度更高,差异有统计学意义(P<0.05),T_2-FLAIR序列的灰白质分界更清晰,差异有统计学意义(P<0.01)。2位医师的定量与定性评估一致性均达中等及以上。结论 与3.0T MRI相比,5.0T MRI在颅脑常规扫描中展现出更高的SNR与CNR(尤其T2WI和T_2-FLAIR序列)、更优的整体图像质量及更少的伪影。
Abstract:Objective To compare the image quality of routine cranial scan sequences between 5.0T MRI and 3.0T MRI. Methods Thirty-five healthy volunteers were recruited to undergo routine cranial imaging at both 5.0T and 3.0T, including T2WI, T1WI, T_2-FLAIR and DWI sequences. Two radiologists independently analyzed the images using a double-blind method. Quantitative metrics included signal-to-noise ratio(SNR) and contrast-to-noise ratio(CNR). Subjective metrics included overall image quality, artifact presence, and gray/white matter delineation. Differences in image quality between field strengths were compared. Intraclass Correlation Coefficient(ICC) was used to assess consistency of quantitative metrics, while, Kappa consistency analysis evaluated subjective metric agreement. Results Quantitative analysis revealed that, for T2WI and T1WI sequences, 5.0T showed significantly higher SNR in the centrum semiovale frontal lobe gray/white matter, putamen, pons, and middle cerebellar peduncle compared to 3.0T MRI(P<0.01); For T_2-FLAIR, 3.0T MRI demonstrated superior SNR in the putamen(P<0.01); 5.0T MRI exhibited better gray/white matter CNR in T2WI and T_2-FLAIR sequences(P<0.01), while, no significant difference in CNR was observed for T1WI(P>0.05). Qualitative analysis showed as follows: 5.0T MRI outperformed 3.0T MRI in overall image quality across all sequences; 5.0T MRI had fewer artifacts and superior gray/white matter delineation in DWI(P<0.05), with clearer gray/white matter boundaries in T_2-FLAIR(P<0.01). Inter-rater agreement for both quantitative and qualitative assessments reached moderate or higher levels. Conclusion Compared to conventional 3.0T MRI, 5.0T MRI demonstrates higher SNR and CNR(particularly in T2WI and T_2-FLAIR sequences), superior overall image quality, and fewer artifacts in routine cranial scans.
[1] BARLETTA V, HERRANZ E, TREABA C A, et al. Quantitative 7-Tesla imaging of cortical myelin changes in early multiple sclerosis[J]. Front Neurol, 2021, 12:714820.
[2] TESTUD B, FABIANI N, DEMORTIèRE S, et al. Contribution of the MP2RAGE 7T sequence in MS lesions of the cervical spinal cord[J]. AJNR Am J Neuroradiol, 2023, 44(9):1101-1107.
[3]王振松,刘建宪,李章柱,等. 5.0T MRI测量健康成人海马结构亚区体积[J].中国医学影像技术,2024, 40(5):648-652.
[4] SHI Z, ZHAO X, ZHU S, et al. Time-of-Flight intracranial MRA at 3 T versus 5 T versus 7 T:Visualization of distal small cerebral arteries[J]. Radiology, 2023, 306(1):207-217.
[5] POHMANN R, SPECK O, SCHEFFLER K. Signal-to-noise ratio and MR tissue parameters in human brain imaging at 3, 7,and 9.4 T using current receive coil arrays[J]. Magn Reson Med, 2016, 75(2):801-809.
[6] GALLICHAN D. Diffusion MRI of the human brain at ultra-high field(UHF):a review[J]. NeuroImage, 2018, 168:172-180.
[7] YIM Y, CHUNG M S, KIM S Y, et al. Wave-controlled aliasing in parallel imaging magnetization-prepared gradient echo(waveCAIPI MPRAGE)accelerates speed for pediatric brain MRI with comparable diagnostic performance[J]. Sci Rep, 2021, 11(1):13296.
[8] VRANIC J E, CROSS N M, WANG Y, et al. Compressed sensing-sensitivity encoding(CS-SENSE)accelerated brain imaging:reduced scan time without reduced image quality[J].AJNR Am J Neuroradiol, 2019, 40(1):92-98.
[9] SU J, NI W, YANG B, et al. Preliminary study on the application of ultrahigh field magnetic resonance in moyamoya disease[J]. Oxid Med Cell Longev, 2021, 2021:5653948.
[10] GU X, XU F, ZHANG L L, et al. A clinical study of amygdala volume changes in medial temporal lobe epilepsy patients[J].Chin J Magn Reson Imaging, 2022, 13(6):36-39.
[11] TANDON V, SENTHILVELAN S, SREEDHARAN S E, et al.High-resolution MR vessel wall imaging in determining the stroke aetiology and risk stratification in isolated middle cerebral artery disease[J]. Neuroradiology, 2022, 64(8):1569-1577.
[12] PILLAI R, CHHEDA A, AGRAWAL S, et al. Skull-base temporal encephalocele:Hidden cause of temporal lobe epilepsy[J]. J Postgrad Med, 2024, 70(2):97-100.
[13] SATI P, REICH D S. 7 Tesla MRI will soon be helpful to guide clinical practice in multiple sclerosis centers-Commentary[J].Mult Scler, 2021, 27(3):364-365.
[14] DAL-BIANCO A, SCHRANZER R, GRABNER G, et al. Iron rims in patients with multiple sclerosis as neurodegenerative marker? a 7-Tesla magnetic resonance study[J]. Front Neurol,2021, 12:632749.
[15] CHOI S, SPINI M, HUA J, et al. Blood-brain barrier breakdown in non-enhancing multiple sclerosis lesions detected by 7-Tesla MP2RAGE delta?T1 mapping[J]. PLoS One, 2021, 16(4):e0249973.
[16] MARTíN-NOGUEROL T, SANTOS-ARMENTIA E, RAMOS A, et al. An update on susceptibility-weighted imaging in brain gliomas[J]. Eur Radiol, 2024, 34(10):6763-6775.
[17]毕京凤,刘欣,瑶张喆,等.超高场7T MRI对三叉神经及邻近血管的显示的应用研究[J].磁共振成像,2023, 14(6):66-70.
[18] WEI Z, CHEN Q, HAN S, et al. 5T magnetic resonance imaging:radio frequency hardware and initial brain imaging[J].Quant Imaging Med Surg, 2023, 13(5):3222-3240.
[19] MAY M W, HANSEN S J D, MAHMUTOVIC M, et al. A patient-friendly 16-channel transmit/64-channel receive coil array for combined head-neck MRI at 7 Tesla[J]. Magn Reson Med, 2022, 88(3):1419-1433.
[20] WILLEMINK M J, COOLEN B F, DYVORNE H, et al. Ultrahigh resolution, 3-dimensional magnetic resonance imaging of the atherosclerotic vessel wall at clinical 7T[J]. PLoS One,2020, 15(12):e0241779.
[21] YIM Y, CHUNG M S, KIM S Y, et al. Wave-controlled aliasing in parallel imaging magnetization-prepared gradient echo(waveCAIPI MPRAGE)accelerates speed for pediatric brain MRI with comparable diagnostic performance[J]. Sci Rep, 2021, 11(1):13296.
基本信息:
DOI:10.20258/j.cnki.1006-9011.2025.08.003
中图分类号:R445.2;R742
引用信息:
[1]王振松,刘建宪,李章柱,等.5.0T MRI与3.0T MRI颅脑常规扫描序列图像质量比较[J].医学影像学杂志,2025,35(08):10-15.DOI:10.20258/j.cnki.1006-9011.2025.08.003.
基金信息: